Pinealon protocol · PepGuide

Course

Course (10–20 days)

50–100u

1–2 mg SubQ (up to 10 mg) · Daily

SubQ, daytime. Some protocols run higher single doses.

Between courses

1–3 courses per year.

Phase	How often	Dose	Units	Notes
Course (10–20 days)	Daily	1–2 mg SubQ (up to 10 mg)	50–100u	SubQ, daytime. Some protocols run higher single doses.
Between courses	–	–	–	1–3 courses per year.

Units at 2 mg/mL. Brain-targeted bioregulator; evidence is largely Russian research.

Cycle & timing

Cycle: 10–20 day course, 1–3×/year.

Timing: Daytime (may be mildly activating).

Where: SubQ, abdomen. Rotate.

What to expect

Proposed cognitive/neuroprotective support over a course; subtle, preliminary evidence.

How much to buy

For 20-day course @ 2 mg/day SubQ:

8

× 5mg vials

4

× 10mg vials

Men & women

Unisex peptide bioregulator, short courses, no sex-specific dosing; minimal human data. Avoid in pregnancy.

Dilution calculator

Set to the guide's typical mix for Pinealon. Change anything to see where to draw.

Vial size

BAC water added

Dose you want

Draw to

100u

Volume

1.00 mL

Strength

2 mg/mL

Doses per vial

2

Assumes a U-100 insulin syringe (100 units = 1 mL). Double-check against the compound's page before you draw.

Recommended mixes

Vial	Water	Strength
5 mg	2.5 mL	2 mg/mL
10 mg	5 mL	2 mg/mL

5 mg: 1 unit = 0.02 mg

Storage

PowderFreeze-dried: -4°F.
MixedReconstituted: 36–46°F, up to the course length.

Don't use if: Active malignancy (theoretical, tissue gene-expression modulation) · Pregnancy and lactation · Hypersensitivity to the peptide

Stop if you notice

Persistent injection-site reaction or sleep disruption
Any unexpected neurological symptom
Pregnancy

Side effects

Generally well tolerated, mild injection-site reaction; possible mild activation if dosed late. Limited human data.

Drug interactions

No well-characterized interactions. Commonly stacked with other bioregulators / nootropic peptides.

Labs

None compound-specific; cognitive tracking if that's the goal

What these labs mean →

Warnings

Limited Western clinical data, most evidence is Russian research. Mild activation possible, dose earlier in the day. Quality varies, request a COA.

Patient education

A short-course, brain-targeted bioregulator; not continuous. Dose earlier in the day to protect sleep. Evidence is preliminary and largely Russian. Request a COA; source quality matters.

These apply on top of the universal safety rules.

Pairs well with

Semax / Selank / P21

cognition

Semax Selank P21 (P021)

Epithalon

pineal/longevity

Epithalon

Other Khavinson bioregulators

Avoid with

Active malignancy

theoretical gene-expression effects

Pregnancy

Can Pinealon + Semax share a syringe?

Can share a syringe. Both are water-based. Combine them if you dose on the same schedule and site.

What it does

Evidence is largely from Russian research; short pulsed courses.

Pinealon is a Khavinson tripeptide (Glu-Asp-Arg, EDR) targeting brain tissue. It is proposed to support neuronal gene expression, protect against oxidative/excitotoxic stress, and aid cognition and circadian regulation.

References

researchdosing peptidedosages PubMed thepeptidereport

From the guide, page 75.