Matrixyl-1
Also: Palmitoyl pentapeptide, Matrixyl 3000
A topical anti-aging peptide that tells skin to make more collagen, a gentler alternative (or partner) to retinol for fine lines. This is a topical cosmetic ingredient: you formulate it into a serum and apply it, you don't inject it.
Use protocol
Well tolerated; pairs with (or substitutes for) retinol with less irritation.
Cycle & timing
Cycle: Continuous topical use; judge at 8–12 weeks.
Timing: Apply to clean skin before heavier creams; can layer under moisturizer/SPF.
Where: Topical, face/neck. Patch-test first.
What to expect
Gradual improvement in fine lines, firmness, and texture over 8–12 weeks of consistent use.
How much to buy
For Most buy pre-formulated % serums for daily use.:
Men & women
Unisex topical cosmetic peptide, used the same by anyone; no systemic dosing. Confirm with a prescriber in pregnancy.