Kisspeptin-10
Tells your pituitary to fire off LH and FSH, which restarts your natural hormone system. Has to be dosed in pulses (like M/W/F), daily shuts it down.
Typical dose
100–200 mcg
4–8u (2.5 mg/mL) · 3.0–6.0u (3.33 mg/mL), M/W/F (pulsatile)
Cycle
30-day cycles, 30-day off
Timing
3×/week SubQ pulsatile, never daily (GP…
Where
Abdomen or outer thigh
Check your units. The units in this table assume 2.5 mg/mL or 3.33 mg/mL, but the guide's recommended mix makes 5 mg/mL. If you mix it that way, your units will be different. Use the calculator to get the right draw for your vial.
Standard
Standard
4–8u (2.5 mg/mL) · 3.0–6.0u (3.33 mg/mL)100–200 mcg · M/W/F (pulsatile)
Community standard SubQ bolus. Daily dosing causes GPR54 desensitisation; pulsatile cadence preserves LH/FSH response.
Fertility
8–16u (2.5 mg/mL) · 6.0–12.0u (3.33 mg/mL)200–400 mcg · M/W/F or pulsatile
HPG restoration. Higher dose for stronger LH/FSH surge. Avoid daily dosing.
Off
30 days
Natural HPG reset.
Dose note: human IV data (George 2011) shows max LH at ~1 µg/kg (~70 mcg/70 kg); ~3 µg/kg gave a reduced response. SubQ bioavailability differs, so don’t escalate past observed LH/libido response.
Cycle & timing
Cycle: 30-day cycles, 30-day off.
Timing: 3×/week SubQ pulsatile, never daily (GPR54 desensitization).
Where: Abdomen or outer thigh.
What to expect
Testosterone and LH/FSH rise within days. Full HPG restoration takes 30+ days. Libido enhancement within 1–2 weeks.
How much to buy
For 4-wk @ 200 mcg × 3/wk:
1
× 5mg vials
1
× 10mg vials
Men & women
Men: Raises LH and testosterone and speeds LH pulses, investigational for low-T and low libido.
Women: The LH/FSH response is hugely cycle-dependent, over 100× stronger just before ovulation. Timing is everything.